CORE BIOMARKER FRAMEWORK
Praxiom Health’s Bio-Age system operates as a sequential, nested progression system where every patient begins their longevity journey at Tier 1 and advances through higher tiers based on their results, needs, and commitment to optimization.
Unlike competitors who offer standalone testing packages, our three-tier system solves the accessibility challenge through what we call “Progressive Engagement Architecture”. It demonstrates value and naturally progresses patients toward advanced interventions as they see tangible results from each tier, maximizing both patient outcomes and revenue potential. Furthermore, it empowers patients to access and store their medical data, keeps it 100% private, and makes it easy to understand and actionable through a scoring system.
Three Tiers of Transformation:
Tier 1: Foundation
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Know your biological age from a single dental visit.
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Chairside saliva tests (pH, CRP, MMP-8) + basic blood panel
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Dynamic Weighting: MMP-8/hs-CRP biomarkers ×2 weighted for cardiovascular synergy
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Oral Biomarkers: Salivary pH, MMP-8, IL-1β
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Systemic Biomarkers: HbA1c, HRV, ELOVL2 methylation
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- Praxiom Health Digital Coach app – the lifestyle companion that keeps track of your health
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Outcome: Your Health Vitality Score and an initial biological age estimate over the next few months.
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Tier 2: Personalization
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Discover which biomarkers matter most for you.
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Advanced microbiome mapping, oxidative stress (8-OHdG), and wearable analytics.
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Outcome: Custom anti-inflammatory protocols and circadian rhythm optimization.
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Tier 3: Mastery
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- Advanced interventions for measurable age reversal.
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Epigenetic and gut–oral axis testing combined with advanced periodontal and microbiome‑focused interventions.
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Outcome: Targeted programmes aiming to improve your biological age trajectory, using L. reuteri probiotics and personalized nutrigenomic plans.
Science Behind the Protocol
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Epigenetic age acceleration causally linked to periodontitis risk via Mendelian Randomization — Clinical Epigenetics, Nov 2025
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Oral microbiome identified as a window into aging and longevity, with calls for an “oral age” clock — Journal of Oral Microbiology, Dec 2025
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Digital biomarkers from wearables validated across nervous, musculoskeletal, and cardiovascular systems for aging — Lancet Healthy Longevity, Jun 2025
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Digital oral biomarkers detect cognitive decline with 85% sensitivity — BMC Public Health, 2023
Technology dashboard
| Feature | Impact |
|---|---|
| Color-Coded Risk Alerts | Real-time patient accessibility |
| Automated Biomodulation | 40% higher compliance vs. traditional protocols |
| Telemedicine Integration | 63% reduction in preventable doctor visits |
Availability of Tier 2 and Tier 3 services may vary by partner clinic and jurisdiction. Please contact us to confirm which options are currently offered in your region.
Begin your journey with a Tier 1 Assessment. Receive: